姚后宗 博士
硕士研究生导师（生物与医药）
学习经历
2017.06 – 2021.10，香港城市大学，化学，博士
2012.09 – 2015.06，苏州大学，药物化学，硕士
2008.09 – 2012.06，苏州大学，药学，学士
工作经历
2022.04 – 今，江西师范大学，健康学院，硕导
2022.02 – 2022.05，香港城市大学深圳研究员，副研究员
2015.12 – 2017.05，香港浸会大学，中医药学院，（高级）研究助理
研究兴趣
铂类金属抗癌药的合成、生物活性与机理研究
科研项目
江西师范大学优秀海归科研启动项目（12021881），2022.04 – 2027.03，50万元，主持
国家自然科学基金面上项目（22077108），2021.01 – 2024.12，63万元，参与
国家自然科学基金面上项目（21877092），2019.01 – 2022.12，67万元，参与
代表性论文
H. Yao,† Z. Wang,† N. Wang, Z. Deng, G. Liu, J. Zhou, S. Chen, J. Shi, G. Zhu.Enhancing circulation and tumor accumulation of carboplatin via an erythrocyte-anchored prodrug strategy.Angew. Chem. Int. Ed.2022, e202203838. [Impact Factor = 16.8]
H. Yao, S. Chen, Z. Deng, M.-K. Tse, Y. Matsuda, G. Zhu.BODI-Pt, a green-light-activatable and carboplatin-based platinum (IV) anticancer prodrug with enhanced activation and cytotoxicity. Inorg. Chem.2020, 59, 11823−11833.
H. Yao, Z. Xu, C. Li, M.-K. Tse, Z. Tong, G. Zhu.Synthesis and cytotoxic study of a platinum (IV) anticancer prodrug with selectivity toward luteinizing hormone-releasing hormone (LHRH) receptor-positive cancer cells. Inorg. Chem.2019, 58, 11076−11084.
H. Yao, G. Zhu. A platinum-based fluorescent "turn on" sensor to decipher the reduction of platinum(IV) prodrugs. Dalton Trans.2022, 51, 5394−5398. [Highlighted as Outside Front Cover]
H. Yao, Y. F. Gunawan, G. Liu, M.-K. Tse, G. Zhu. Optimization of axial ligands to promote the photoactivation of BODIPY-conjugated platinum (IV) anticancer prodrugs. Dalton Trans.2021, 50, 13737−13747.
H. Yao, F. Jiang, A. Lu, G. Zhang.Methods to design and synthesize antibody-drug conjugates (ADCs). Int. J. Mol. Sci. 2016, 17, 194.
H. Yao, F. Liu, J. Chen, Y. Li, J. Cui, C. Qiao.Antischistosomal activity of N,N'-arylurea analogs against Schistosoma japonicum. Bioorg. Med. Chem. Lett.2016, 26, 1386−1390.
S. Ni,†H. Yao,† L. Wang, J. Lu, F. Jiang, A. Lu, G. Zhang.Chemical modifications of nucleic acid aptamers for therapeutic purposes.Int. J. Mol. Sci. 2017, 18, 1683.
姚后宗，尹伟，陈晶磊，乔春华. 一种氟代丁酸腺苷衍生物的合成.有机化学. 2014, 34, 1222−1226.
代表性论著
Z．Deng,† H. Yao,† Z. Wang, G. Zhu.Platinum anticancer drugs: Targeting and delivery, in Comprehensive Inorganic Chemistry III (Eds.: J. Reedijk, K. Poeppelmeier), Under Proof.
联系方式
地址：江西省南昌市紫阳大道99号江西师范大学健康学院
电话：18070595232
E-mail：yaohz@jxnu.edu.cn