江西师范大学黄娇芳

黄娇芳

江西新余人，理学博士，硕士和博士生导师。入选国家高层次青年人才。担任Front Bioeng Biotech、BioDesign Res、Biomaterials Translational、Green Synthesis and Catalysis等SCI期刊的编委和客座副主编。担任中国化工学会生物化工专委会青年委员和上海市化学化工学会生物技术与工程专业委员会委员。担任Chem Eng J、Biotechnol Adv、Syn Syst Biotechno等多个期刊的审稿人。

主要学习经历：

2001.9-2005.7 北京林业大学生物科学国家理科基地班生物科学本科

2005.9-2011.3 上海交通大学生命科学技术学院微生物学博士

2009.8-2010.6 瑞士洛桑大学微生物学系联合培养博士

主要工作经历：

2011.5-2014.9 中国科学院上海高等研究院助理研究员

2014.10-2019.10 上海科技大学博后、助理研究员

2019.11-至今华东理工大学特聘研究员，博导

2023.06-至今江西师范大学特聘教授，博导

研究兴趣、领域：

主要从事微生物合成生物学及工程活体材料研究。结合生物工程、合成生物学、纳米材料等研究微生物（及其被膜），开发工程活体材料并应用于连续催化、环境能源和生物医药等领域。

热忱欢迎生物工程、生物科学、生物技术、生物化工等相关方向，并对交叉学科有好奇心与探索欲的新同学加入！

同时，课题组长期招收博士后及研究助理等工作人员，待遇从优，欢迎加入！

承担项目情况：

国家重点研发计划“合成生物学”重点专项（子课题），2020.11-2025.10；
国家自然科学基金面上项目，2019.01-2022.12，主持；
国家自然科学基金青年基金项目，2015.01-2017.12，主持；
上海市自然科学基金项目，2019.7- 2022.6，主持；
上海市自然科学基金项目，2022.4- 2025.3，主持

代表性论文：

[1] Jiaofang Huang, Suying Liu, Chen Zhang, Xinyu Wang, Jiahua Pu, Fang Ba, Shuai Xue,Haifeng Ye, Tianxin Zhao, Ke Li, Yanyi Wang, Jicong Zhang, Lihua Wang, Chunhai Fan,Timothy K. Lu and Chao Zhong*. Programmable and printable Bacillus subtilis biofilms as engineered living materials. Nature Chemical Biology. 2019.1, 15(1): 34–41. (Q1, Top期刊.ESI高被引论文).

[2] Chen Zhang, Jiaofang Huang (并列一作), Jicong Zhang, Suying Liu, Mengkui Cui, Bolin An, Xinyu Wang, Jiahua Pu, Tianxin Zhao, Chunhai Fan, Timothy K. Lu, Chao Zhong*. Engineered Bacillus subtilis biofilms as living glues. Materials Today. 2019.9, 28: 40-48. (Q1, Top期刊, IF=31.0).

[3] Jiahua Pu, Yi Liu, Jicong Zhang, Bolin An, Yingfeng Li, Xinyu Wang , Kang Din, Chong Qin, Ke Li, Mengkui Cui, Suying Liu, Yuanyuan Huang, Yanyi Wang, Yanan Lv, Jiaofang Huang, Zongqiang Cui, Suwen Zhao, Chao Zhong. Virus Disinfection from Environmental Water Sources Using Living Engineered Biofilm Materials. Advanced Science. 2020,7, 1903558. 1-8. (Q1, Top期刊, IF=17.5).

[4] 常璐，黄娇芳*，董浩，周斌辉，朱小娟，庄英萍*. 合成生物学改造微生物及生物被膜用于重金属污染检测与修复.中国生物工程杂志China Biotechnology.2021,41(1):62-71.

[5] Hao Dong, Wenxue Zhang, Qize Xuan, Yao Zhou, Shengmin Zhou*, Jiaofang Huang*, and Ping Wang. Binding Peptide-Guided Immobilization of Lipases with Significantly Improved Catalytic Performance Using Escherichia coli BL21(DE3) Biofilms as a Platform. ACS Applied Materials & Interfaces. 2021,13,6168-6179. (Q1, Top期刊, IF=10.4).

[6] Hao Dong, Wenxue Zhang, Shengmin Zhou, Jiaofang Huang*, Ping Wang*. Engineering bioscaffolds for enzyme assembly. Biotechnology Advances. 2021.107721. (Q1, Top期刊, IF=17.7).

[7] Muhammad Zubair Mohsin, Rabia Omer, Jiaofang Huang#*, Ali Mohsin, Meijin Guo, Jiangchao Qian, Yingping Zhuang*. Advances in engineered Bacillus subtilis biofilms and spores, and their applications in bioremediation, biocatalysis, and biomaterials. Synthetic and Systems Biotechnology. 2021, 6(3):180-191. (Q1, Top期刊, 国产卓越期刊)

[8] Rabia Omer, Muhammad Zubair Mohsin, Ali Mohsin, Bilal Sajid Mushtaq, Xumeng Huang, Meijin Guo, Yingping Zhuang and Jiaofang Huang*. Engineered bacteria-based living materials for biotherapeutic applications. Frontiers in Bioengineering and Biotechnology. 2022.10.870675. (Q1, IF=6.1)

[9] Suying Liu#, Jiaofang Huang#*, Chen Zhang, Lihua Wang, Chunhai Fan, and Chao Zhong*. Probing the Growth and Mechanical Properties of Bacillus subtilis Biofilms through Genetic Mutation Strategies. Synthetic and Systems Biotechnology. 2022.7(3): 965-971. (Q1, Top期刊, 国产卓越期刊)

[10] 专著：生物基可降解材料的研究与应用（赵黎明主编）. 上海科学技术出版社. 2022年8月出版. 第四章《工程活体材料》. 书刊登记号ISBN：978-7-5478-5741-0.

[11]黄娇芳，童阿康，罗远婵，钱江潮，吴辉，王启要，庄英萍*. 微生物学全英文教学的意义、问题以及促研促教的实践探索. 生物工程学报. 2022,38(07).

[12] Lingfan Zhang*, Sichao Lou , Xiangrui Hao, Hongyan Zhang, Wenqing Zhang, Xin Liu, Jiaofang Huang*. Highly-porous and excellent-capacity zirconium-chitosan composite with superior Sb(III)/Sb(V) removal performance. Separation and Purification Technology. 2022.303. 122253. (Q1, Top期刊, IF=9.1)

[13] Muhammad Zubair Mohsin #, Jiaofang Huang #* , Muhammad Hammad Hussain, Waqas Qamar Zaman*, Zebo Liu, Salim-ur-Rehman d , Yingping Zhuang, Meijin Guo, Ali Mohsin*. Revolutionizing bioremediation: Advances in zeolite-based nanocomposites. Coordination Chemistry Reviews. 2023.215253. (Q1, Top期刊, IF=20.6)

[14] 徐燕，赵纯骏，娄思雨，彭孜怡，周斌辉，陈林，黄元培，项沁媛，黄娇芳*. 土壤污染修复中活体功能材料的应用研究. 生物加工过程. 2023.21(4):379-389,438.

[15] Yi Liu#, Mengyao Wu, Anqi Kang, Xiehaoran Zhang, Ronghui Xie, Yuanpei Huang, Jiaofang Huang, Lien-Yang Chou,* and Chao Zhong*,Living Seed Materials Made by Metal–Organic Framework-Encapsulated Bacillus Subtilis Spore, Advanced Functional Materials,2023.2309288(Q1, Top期刊, IF=18.5)

[16] Xiaojuan Zhu, Qinyuan Xiang, Lin Chen, Jianshu Chen, Lei Wang, Ning Jiang, Xiangrui Hao, Hongyan Zhang, Xinhua Wang, Yaqian Li, Rabia Omer, Lingfan Zhang, Yonghong Wang, Yingping Zhuang, Jiaofang Huang*. Engineered Bacillus subtilis Biofilm@Biochar Living Materials for In-situ Sensing and Bioremediation of Heavy Metal Ions Pollution. Journal of Hazardous Materials.2024.465.133119. (Q1, Top期刊, IF=13.6).

[17] Muhammad Zubair Mohsin#, Ali Mohsin#*, Waqas Qamar Zaman, Xiaojuan Zhu, Xihua Zhao, Zain Abbas, Muhammad Hammad Hussain, Ali Shan, Salim-ur-Rehman, Muhammad Asif Nawaz, Rabia Omer, Yingping Zhuang, Meijin Guo, Jiaofang Huang*. Efficient Toluene Degradation using Bacillus subtilis Biofilm Supported Mn-Ce/Zeolite Catalysts. Green Synthesis and Catalysis. 2024.01.006. (Q1, Top期刊, IF=8.3).

[18] Ning Jiang, Kui Zhao, Chengcheng Liu, Xiaojuan Zhu, Xumeng Huang, Lin Yang, Xiaoping Yi, Yingping Zhuang, Bangce Ye, Jiangchao Qian, Jiaofang Huang*. Tumor Microenvironment Responsive Multifunctional Smart Living Materials based on Engineered Bacteria for Inducing Macrophage Polarization to Enhance Tumor Immunotherapy. Chemical Engineering Journal. 2024.150820. (Q1, Top期刊, IF=15.1).

[19] Yi Xue, Chenjie Yu, Han Ouyang, Jiaofang Huang*, and Xue Kang*. Uncovering the Molecular Composition and Architecture of the Bacillus subtilis Biofilm via Solid-State NMR Spectroscopy. Journal of the American Chemical Society. 2024.4c0089. (Q1, Top期刊, IF=15.1).

[20] Ning Jiang, Wanqing Ding, Xiaojuan Zhu, Jianshu Chen, Lin Yang, Xiaoping Yi, Yingping Zhuang, Jiangchao Qian, Jiaofang Huang*. Lipid-encapsulated Engineered Bacteria Living Materials Inhibit COX-2 to Enhance DOX Toxicity. BioDesign Research. 2024,6,0038.

[21]Xiaojuan Zhu, Jianshu Chen, Jian Luo, Xue Liu, Yan Xu, Lin Chen, Hao Dong, Lingfan Zhang, Lin Yang, Nin Jiang, Xumeng Huang, Ali Mohsin, Xiaoping Yi, Yonghong Wang, Yingping Zhuang, Xuehong Zhang, Ke Zhang, Lixin Zhang, Chao Zhong, and Jiaofang Huang*. Functional Living Materials for Virus Disinfection Based on Engineered Bacillus subtilis Biofilm by Displaying Viral Affinity Peptides and Expressing Protease. Advanced Functional Materials. 2024, 2407072.(Q1, Top期刊, IF=18.5).

[22]Ning Jian, Mingyan Jian, Jianshu Che, Xiaoping Y, Yingping Zhuan, Jiangchao Qian, Jiaofang Huang*. Living hybrid material based on probiotic with photothermal properties inhibits PD-L1 expression after tumoricidal Photothermal Therapy. Biomaterials Translational. 2025, 6(1), 73-84.

主要发明专利：

[1] 黄娇芳，孙立洁，陈祥松，袁丽霞，王纪，吴金勇，朱薇薇，王刚，姚建铭，史吉平，魏东.一种产L-肉碱的大肠杆菌基因工程菌的构建及酶转化方法. ZL201510278530.7.

[2] 钟超，黄娇芳，张琛，刘苏莹. 作为工程化活体材料的可编程和可打印的生物膜. CN201980067767.7.

[3] Chao Zhong, Jiaofang Huang, Chen Zhang, Suying Liu. Programmable and printable biofilms as engineered living materials. 美国专利US17169504.

[4] 钟超，张琛，黄娇芳，张继聪.一种活体水下粘合材料及其用途. ZL201810519230.7.

[5] Chao Zhong, Chen Zhang, Jiaofang Huang, Jicong Zhang. Engineered biofilms. 美国专利 US2021079049(A1).

[6] 黄娇芳，钟超，辛美玲. 一种工程菌的混合物、用于感应和吸附重金属污染物的试剂盒和处理方法. ZL202011589294.8.

[7] 黄娇芳，项沁媛，朱小娟，郝祥蕊，张红艳，庄英萍. 一种感应和吸附多种重金属离子的工程菌和工程化生物被膜. ZL202310553773.1.

[8] 黄娇芳，蒋宁. 一种基于 ECN 的自裂解药物递送平台、构建方法及应用. CN202410409102.2. （申请日：2024.04.07）

[9] 黄娇芳，朱小娟，徐燕. 一种基于枯草芽孢杆菌生物被膜的工程活体材料用于病毒的吸附和灭活. CN2024105554248（申请日：2024.05.07）

[10] 黄娇芳，钱江潮，赵奎，孙晓波，丁万晴，胡瑾怡.一种提高定制化功能化单链DNA产量的发酵生产方法. CN202410609758.9. （申请日：2024.05.16）

[11] 黄娇芳，钱江潮，丁万晴，胡瑾怡，蒋宁. 一种靶向肿瘤细胞的带适配体DNA纳米结构的生物制备方法及应用. CN202410627908.9.（申请日：2024.05.21）

[12] 黄娇芳，朱小娟，蒋宁，陈建树. 一种枯草芽孢杆菌展示多酶级联催化生产活性寡糖和单糖治疗肠炎的方法及应用. CN202410636114.9.（申请日：2024.05.22）

[13] Jiaofang Huang, Ning Jiang. PLATFORM OF DRUG DELIVERY BASED ON SELF-LYSIS OF ECN, CONSTRUCTING METHODAND USE OF THE SAME. 美国专利申请号US19/015767.（申请日：2025.01.10）

[14] 黄娇芳,王蕾,蒋宁. 一株蒙氏假单胞菌psm006 及其应用. CN2025101957901.（申请日：2025.02.21）

[15] Jiaofang Huang, Xiaojuan Zhu, Ning Jiang, Jianshu Chen. ENGINEERED BACTERIA, ENGINEERED BIOFILMS, AND LIVING MATERIALS BASED ONBACILLUS SUBTILIS. 美国专利申请号19/078339（申请日：2025.03.13）

[16] 黄娇芳,王蕾,杨丽欣. 贝莱斯芽孢杆菌bvx001、复合微生物菌剂和应用. CN202510386800X.（申请日：2025.03.31）

联系方式：

13564239725@163.com